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Chunk #87 — METHODS — Statistical analysis — Tissue and cell type enrichment

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Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.
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To further evaluate whether the genomic loci implicated in depression are enriched in any particular cell type, we intersected common depression risk variants with two recent epigenomic maps of cell-specific open chromatin57,58 using a LD score partitioned heritability approach59 (Figure 3B).