CIs. Three SNPs showed evidence for associations in the follow-up study with p-values between 0.02 and 0.05. Their corrected OR estimates are less than the uncorrected OR estimates. The selection adjusted CIs are wider than the unadjusted CIs. However, the selection adjusted CIs for these SNPs exclude 1 as well. The corrected point estimates and CIs are more consistent with those from the replication studies. Three SNPs failed to show significance in the follow up study, though they had p-values from 4.24 × 10−6 to 1.64 × 10−5 in the GWAS. Their corrected OR estimates are much smaller than the uncorrected OR and closer to the replication OR estimates. The selection adjusted CIs for these SNPs are much wider than the unadjusted CIs and all include 1.
