As described in detail elsewhere, baseline LRs for probands were determined through alcohol-related changes in subjective feelings of intoxication, standing steadiness, and hormones (e.g., cortisol) at breath alcohol concentrations of ~60 mg/dL, as measured by an Intoximeter (Eng et al., 2005; Schuckit and Gold, 1988; Schuckit and Smith, 1996). Across multiple sessions, all subjects consumed 0.75 ml of alcohol or placebo and were evaluated over three hours as their blood alcohol concentrations (BACs) rose, peaked and decreased to close to zero. Z-scores were used to combine data into one overall LR score where lower values reflected lower LRs per drink. At T15, probands completed the Self-Report of the Effects of Alcohol (SRE) questionnaire regarding the number of drinks required for effects during three life epochs (the first five times of drinking [SRE5], the most recent three months, and their period of heaviest drinking). SRE5 and total scores incorporating all three epochs (SRET) were generated by summing the number of drinks required for up to four effects (feeling first effect, slurring speech, unsteady gait, or unwanted falling asleep), and dividing that
