We have been continuously developing the coexpression database, COXPRESdb (coexpression database), providing high-quality coexpression data with new metrics (16,17) and various analysis frameworks (18–20). For example, when a user is interested in a particular gene, the coexpressed gene list for the target gene is available from the coexpressed gene page. When a user is interested in a particular function, the EdgeAnnotation tool, NetworkDrawer tool and the GO network page easily bring all the genes associated with the function along the coexpressed genes. The information and the tools can be used for the 11 species (human, mouse, rat, monkey, dog, chicken, zebrafish, fly, nematode, budding yeast and fission yeast) in COXPRESdb, and users can evaluate the reliability of the coexpression information by inspecting coexpression in orthologous genes. Some other features and the overview of COXPRESdb are available at http://coxpresdb.jp/overview.shtml.
