on mild or moderate impairment and dementia. Lastly, we would like to utilize a broader range of baseline predictors, including environmental variables (e.g., socioeconomic status, traumatic experiences), neuropsychological test performance, endophenotypic measures (e.g., neurophysiological [EEG and ERP]), and genetic data. In sum, COGA’s extensive assessment of these domains provides a rare opportunity to search comprehensively for the long-term harbingers of alcohol use and consequences among its oldest members.