High-scoring phastCons elements (LOD > 680, top 1%) cover 3% (38,040/1,244,409 bp) of the genomic space that includes FTO and IRX5 (hg19, chr16:53731249–54975288), whereas on average, only 0.5% +− 0.6 of genomic intervals with the same length are occupied by such high-scoring phastCons elements. Genomic intervals of the same size of the FTO/IRX3 locus were generated every 10kb for each chromosome. The FTO/IRX5 is at the top 1% intervals containing high-scoring phastCons elements.
