Similarly, in the FTO/IRX5 interval, 9% of the base pairs have phastCons score above 0.9 (range: 0.0–1.0), whereas 14,164 intervals from all chromosomes of the same size offset by 200kb contain only 3.8% +− 1.9 of such high-scoring base pairs. At 9%, the FTO/IRX5 is at the top 2% intervals with the most conserved base pairs.