the central tendencies of differences between the groups' connectivity pattern, the current FC-VM/VSM-PLS examined individual differences and revealed that those patients who do better on clinical memory measures tend to rely on the pattern most associated with controls whereas those patients who do worse on memory testing tend to rely on the altered pattern that best characterizes the patient group as a whole. Therefore, these findings suggest that the greater the divergence of DMN connectivity from healthy controls, the worse episodic memory capacity in patients with mTLE. This finding is in line with a recent study showing that both decreased PCC–HC and increased hippocampal–entorhinal connectivity was associated with worse episodic memory capacity in patients with mTLE (Voets et al., 2014).
