with worse episodic memory capacity (see Fig. 2 and Table S1 for BSRs). As the right temporal pole also showed decreased grey matter volume in patients with R-mTLE, a possible explanation for this involvement might be a higher spike and seizure propagation rate to the right temporal pole in patients with R-mTLE than in patients with L-mTLE. A recent study found that interictal epileptic spikes impair episodic memory function (Kleen et al., 2013) and it might therefore be that the involvement of the right temporal pole reported here might have been influenced by pathological brain activity. However, we found the same pattern separation in an additional analysis examining patterns associated with better and worse verbal memory capacity in patients with L-mTLE (L-mTLE, FC-VM-PLS, p = 0.03, see Table S2). For patients with R-mTLE, this additional analysis did not reach significance, nonetheless, the pattern separation was still visible (R-mTLE, FC-VSM-PLS, p = 0.4, see Table S2). Whereas the previous FC-PLS examined the central tendencies of differences between the groups' connectivity pattern, the current FC-VM/VSM-PLS examined individual differences and revealed that those patients who do better on clinical memory measures tend to rely on the pattern most associated with controls whereas those
