We found that functional connectivity of the DMN indicated verbal (FC-VM-PLS, p = 0.01) and visuospatial memory capacity (FC-VSM-PLS, p = 0.04, see Fig. 2 and Table S1 for BSRs) in this patient cohort. Strikingly, the same functional connectivity patterns that separated healthy controls from patients before were now associated with better and worse episodic memory performance in the patient group. That is, connections associated with better verbal and visuospatial memory capacity mainly integrated the material-specific MTL into the posterior part of the DMN (VM: 5 of 7, VSM: 4 of 11 significant connections), whereas connections that were associated with impaired verbal and visuospatial memory capacity tended to be intrahemispheric connections and involve DMN nodes of the prefrontal cortex (VM: 11 of 18, VSM: 8 of 22 significant connections). Further, connectional involvement of the right temporal pole was also associated with worse episodic memory capacity (see Fig. 2 and Table S1 for BSRs). As the right temporal pole also showed decreased grey matter volume in patients with R-mTLE, a possible explanation for this involvement might be a higher spike and
