The PhenX (https://www.phenxtoolkit.org/) Acute Subjective Responses to Alcohol, based on the Self-Rating of the Effects of Alcohol (SRE) for (Schuckit et al., 2008), measures youths’ subjective effects to alcohol use following the participant’s first 5 times of drinking, recent 3 months, and over their heaviest period of use. The SRE has been shown to be a robust and reliable measure with regards to the development of alcohol problems (Ray et al., 2011; Schuckit et al., 2008). In Ray et al.’s 2011 paper, SRE scores account for as much as 25% of the variance in Alcohol Use Disorders Identification Test scores and highly correlate (r = 0.70–0.80) with interview format scores. The self-administered questionnaire asks participants to report about their drinking behaviors during these time periods (first 5 times drinking, recent 3 months, and period of heaviest use) and to list the number of standard drinks (10–12 g of ethanol) required for the experience of each potential effect of alcohol, including feelings of intoxication, slurred speech, feeling unsteady or developing a stumbling gait, and unwanted falling asleep (5).
