The Acute Subjective Response to Marijuana scale, developed for adolescents in the Cannabis Twin Study (Agrawal et al., 2014, Agrawal et al., 2013), was selected to measure the participant’s subjective response to cannabis following the youth’s first or second exposure. Early subjective response has been linked with onset of cannabis use disorder and cannabinoid genetics in adolescents and young adults (Agrawal et al., 2014). The assessment asks the participant to report his/her subjective responses on a scale from 1 “not at all,” 2 “somewhat,” 3 “a little,” to 4 “a lot,” including 11 questions about taste, coughing, dizziness, feeling relaxed, headache, heart racing, muscle tremble or feeling jittery, burning in throat, feeling confused, nausea, and sensations of pleasure (i.e. rush or buzz). Youth are only queried about each of these categories if they endorsed hearing of the substance and using the substance at least once in their lifetime.