Chunk #23 — Result — Functional impact of genetic risk factors in transcriptomic signatures

Source

A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles.

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We next hypothesized that brain disorder-associated genes are dysregulated in corresponding disorders. Therefore, we assessed whether brain disorder-associated genes are differentially regulated in postmortem brains with brain disorders (Methods)2.