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Chunk #10 — Methods — Measures — Lifetime AUD severity

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Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers.
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The AUDADIS uses 21 items to assess the 11 alcohol dependence and abuse criteria according to DSM-IV (American Psychiatric Association., 2000). As the lifetime dependence and abuse criteria were unidimensional in this sample (Shmulewitz et al., 2010), we created a quantitative measure of AUD severity by counting the number of lifetime criteria endorsed; AUD severity ranged from 0–11. Test-retest reliability of lifetime AUDADIS alcohol criterion count is excellent in general population samples (ICCs=0.86–0.89 (Hasin et al., 2007)).