The genome-wide MvA plot displayed difference of DNA methylation levels between two groups of all the genes according to their average DNA methylation levels e.g. control-undifferentiated vs. control-differentiated, control-differentiated vs. alcohol-differentiated. There was strong diversification of methylation during differentiation (comparing the undifferentiated with the differentiated). Such differentiation-related diversification was greatly reduced when treated with alcohol (comparing the undifferentiated with the differentiated + alcohol) (Figure 4), indicating alcohol prevented the diversification of DNA methylation
