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Chunk #23 — Discussion — Evidence for the hippocampal coupling account

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The hippocampus is coupled with the default network during memory retrieval but not during memory encoding.
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connections between HF and components of the DMN at the neuroanatomical level [43], [44], but also at the neurofunctional level [45], [46]. Yet, despite these findings linking HF to the DMN, the current results clearly show that, at least during memory performance, the coherence between DMN and HF is not universal, but dependent on the type of memory operation, either encoding or retrieval. More generally, the current findings are in favor of the hippocampal coupling hypothesis and indicate that HF is not among the core DMN regions. Further research is necessary to characterize the precise conditions under which HF is coupled to the DMN and when it is not.