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Chunk #22 — 3. Results — 3.1 RNA-seq results

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Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.
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Expression of many ion channel genes was altered (Table 3): 32 of 67 potassium channels were differentially expressed, with 21 increased and 11 decreased; Kcnj6 was increased 30%. Twelve calcium channels showed altered expression, with equal numbers increased and decreased. Three sodium channels were increased and 6 decreased. Two chloride channel genes were increased and 4 decreased.