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Chunk #23 — 3. Results — 3.1 RNA-seq results

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Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.
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Many genes involved in myelin production were decreased by 30 to 60% (Supplementary Table 1). Similar decreases in multiple brain regions have been reported multiple times in human post-mortem studies (Liu et al., 2006a; McClintick et al., 2013) and animal models (Alfonso-Loeches et al., 2012).