genes, in particular those associated with early oligodendroglial and astroglial lineage progression, which were uniformly down-regulated in the SCZ hGPCs relative to their normal controls (Figures 4C and 4F). These included a coherent set of the key GPC lineage transcription factors OLIG1, OLIG2, SOX10, and ZNF488, as well as genes encoding stage-regulated proteins involved in myelination such as GPR17, UGT8, OMG, and FA2H (Figure 4G; see Table S2 and Figures S3 and S4 for detailed gene expression data).