Chunk #19 — MATERIALS AND METHODS — Statistical model — QuantiSNP: an Objective Bayes Hidden-Markov Model — Posterior measures

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QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data.

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This posterior measure compares the evidence for the region zi:j being in hidden state k in comparison to all other sequences in which no part of this region is in this hidden state. The greater the value of BF, the more confidence we have in the event being of significance. We ignore all called events whose ratio is below a user-defined threshold.