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Chunk #16 — METHODS — General procedure

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Adaptation of Subjective Responses to Alcohol is Affected by an Interaction of GABRA2 Genotype and Recent Drinking.
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Testing in each session comprised three 45 min blocks during which multiple tasks were administered in the same order (Figure 1); only results for subjective perceptions are reported here. Block 0 (Baseline) was obtained just prior to the infusion; subjects were aware that they had not received any alcohol at this point in the protocol. The alcohol or placebo infusion was then initiated, and Block 1 began either 20 min later (placebo session) or after the 60 mg/dL alcohol clamp was established and stable for 5 minutes (19.4 ± 0.04 min (mean ± SEM)). Block 2 began 105 min after the start of Block 1.