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Chunk #54 — Online methods — Multiple Measurements

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Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.
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proportion of variance due to the GRS in the absence of measurement error, and β/(α+β) is the proportion of variance in BP due to measurement error. Fitting a linear regression model to 1/H as a function of 1/k, we can then use the estimated intercept (α) and regression coefficient (β) to estimate the error variance and variance due to the GRS in the absence of measurement error.