We additionally tested GRS constructed by weighting different subsets of identified BP-associated SNPs (i.e., identified for SBP, for DBP, and for PP, constructed as described above). Hypertension onset here was defined as the first hypertension treatment time, or the first time either SBP≥140 or DBP≥90 occurred in an individual and was maintained for the next subsequent BP measurement. Individuals were left censored at their first measurement (and not included if already meeting the hypertension diagnosis criterion), and right censored at their latest measurement if not hypertensive.
