habituation effect is specific to the alcohol cues, and is not due to a general decrease in task novelty (see supplementary materials). The relatively small sample size is another limitation, but is mitigated by the within-subject design for the primary analyses, presumably increasing the power to detect true associations. The genotype and correlational analyses, however, should be interpreted with caution until the results are replicated within larger samples. It should also be noted that the results obtained from the prospective genotyping groups may be different in a genetically unselected sample. Thus, future research is needed to validate these findings in larger, genetically unselected samples.
