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Chunk #9 — METHODS & MATERIALS — Suicidal ideation and attempt

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Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism.
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All participants were queried about (a) whether they had “ever thought about taking their own life” (ideation: SI) and (b) whether they had “ever tried to kill” themselves (attempt: SA). SA was queried regardless of a history of SI. Importantly, SI and SA items were not nested within the diagnostic section for major depressive disorder (MDD) although individuals who reported SI and SA in that section were coded accordingly as having reported the behavior. For the current analyses, individuals reporting any SA (e.g. even those reporting drug-related SA, 14%) were included. The distribution of ages of onset for SI and SA are shown in Supplemental Figures S2A and S2B respectively.