and one study reported increased latency in adult alcoholics. These studies have not clarified if the N400 amplitude reductions were specific to differences in priming related activations. Hence, the current study was conducted to examine the semantic priming effects on N400 in male adult alcoholics. A recent study from our laboratory (Roopesh et al., 2009) showed lack of attenuation of N400 amplitude for primed stimulus in high risk offspring of alcoholics.