al., 2008), suggested diminished cognitive control function and weakened cognitive control upon craving and motivation in heroin users. Taken together, the abnormality of functional connectivity in heroin users observed here supports the theories of addiction positing that the drug craving and motivation are enhanced in the addicted state, whereas the strength of cognitive control is weakened (Baler and Volkow, 2006; Bechara, 2005; Everitt and Robbins, 2005; Garavan and Hester, 2007; Goldstein and Volkow, 2002).
