Although it seems unlikely that SNP rs1344706 directly increases risk for schizophrenia, the association and expression data collectively are consistent with possible functional effects at rs1344706 itself. The A allele shows significantly higher expression than the C allele in control dorsolateral prefrontal cortex. The A allele is associated with schizophrenia, and expression in schizophrenic case dorsolateral prefrontal cortex is increased relative to that in controls, although this last difference does not achieve statistical significance.
