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Chunk #11 — Method — DNA Extraction, Genotyping, Quality Control

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STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.
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The FKBP5 SNP rs1360780 was selected based on our prior studies of FKBP5 polymorphisms within this population (13, 45–47). Genotype data was available for 43 participants (11 with PTSD, 32 controls). Participants were categorized into two groups based on genotype, i.e., how many “risk” alleles comprised their genotype, based on previous studies. For this SNP, individuals were categorized as having either 0/1 or 2 copies of the risk (T) allele. Within this sample, 26 had CC or CT genotype, 17 had TT genotype.