To examine associations between structural and functional connectivity, a whole-brain analysis was conducted on the hippocampal functional connectivity. Similarly, the preprocessed time series were averaged across voxels within the hippocampus mask. The Pearson’s correlation coefficient was calculated between the hippocampus seed time series and voxel-wise time series of the whole brain with the motion censoring procedure. After Fisher’s transformation, the association was measured using the cingulum FA as a regressor on the hippocampal functional connectivity. All resulting maps were family-wise error (FWE) corrected at p < 0.05 for the whole brain via Monte-Carlo simulations with AFNI’s 3dClustSim program.
