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Chunk #9 — Method — Resting State Functional Connectivity Analyses

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STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.
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Functional connectivity between the hippocampi and ACC was evaluated by using temporal correlation of time series. Specifically, the preprocessed time series were averaged across voxels within the hippocampus and ACC masks separately. The Pearson’s correlation coefficient was calculated between two averaged time series for each participant. Note that the motion censoring (“scrubbing”) procedure (44) was performed by excluding frames with excessive head motion based on the Euclidian norm of the first time differences of motion estimates (> 0.25 mm) during the analysis. Then, these correlation coefficients were converted to z-values using Fisher’s transformation. Finally, these z-values were entered into second-level random-effects analyses.