including animal models and in vitro cultures of non-relevant cell lines (such as 293T or HeLa cells), which recapitulate only some of the specific traits of human disease (Eglen and Reisine, 2011, Pouton and Haynes, 2005), with the potential to reverse the current trend of huge investments by the pharmaceutical industry yielding few therapeutic compounds entering the market (Mullard, 2015, Scannell et al., 2012).