in subjects using cocaine, marijuana and alcohol, but this hyper-connectivity was observed after abstinence periods longer than 4 days (Wang et al., 2015). These rsFNC dysfunctions likely specify effects that may be commonly linked to multiple substances of abuse where hyper-connectivity during withdrawal follows an initial hypo-connectivity during consumption. Despite using DSM-IV-TR Axis I to exclude subjects with alcohol problems in controls, the absence of an AUDIT score for the CTR subjects limits our capacity to perform a more thorough interpretation of these results.
