P<0.05 threshold). Second, we calculated that at most 132 positive replications would be expected out of statistical power (59% on average for the 225 attempts in East Asians, Table S5). The 103 observed replications thus correspond to an effective replicability rate of 77.9%, which suggests that a noticeable fraction of GWAS associations are shared across Eurasians. Again, we found no heterogeneity across diseases (Table S7).
