Brain tissue samples (frontal cortex) from neurologically healthy control individuals were obtained from the National NeuroAIDS Tissue Consortium (NNTC), the Kathleen Price Bryan Brain Bank (KPBBB) at Duke University, and the Oregon Brain Bank. PBMCs from healthy living participants were purchased from Seracare Bioservices, Cellular Technology Ltd., and also provided by the Duke Human Vaccine Institute. All samples used in this analysis were of European ancestry. Sample demographics are included in Table S1. PBMCs obtained from living participants were completely de-identified and obtained according to standards set forth by the Duke University Institutional Review Board.