Our analysis revealed two notable variants: rs9839776 (P=3.01×10-7) in SOX2OT (SOX2 overlapping transcript) and rs17030795 (P=5.84×10-6) in PPP3CA (protein phosphatase 3, catalytic subunit, alpha isozyme) (Table 2). Two additional signals emerged from the analysis focused on European replication samples only: rs1523921 (P=5.76×10-6) located between CUL3 (cullin 3) and FAM124B (family with sequence similarity 124B) and rs1886797 (P=8.05×10-6) located 18kb from SPATA13 (spermatogenesis associated 13) (Table S5). Four signals were in neurodevelopmental genes regulating synapse and neuronal network formation (SYN2, NCAM2, CNTNAP2 and CTNNA2; Table 2).
