In summary, there is growing use of molecular genetic studies to compare the identity and strength of common SNP associations in males and females, the SNP‐based heritability of psychiatric disorders by sex, and the burden of both common polygenic risk and rare variants of large effect in affected males and females. Epigenetic and transcriptomic analyses have suggested differences in DNA methylation and gene expression in male and female brains, but the potential impact of these differences on risk and expression of psychiatric disorders remains an open question.
