Google Scholar, and the portal is accessed on average by ∼1600 new visitors monthly, with a total of ∼ 425 000 pageviews and >20 000 full TCRD database downloads (as of 3 September 2020). TCRD has been enhanced by inclusion of new data types and data from emerging resources, which were prepared for machine-learning readiness. The scope of TCRD has also been expanded, moving past the initial area of focus of the druggable genome to aggregate data about the entire human proteome. The first published version of Pharos was based on TCRD version 3.0, the latest version uses TCRD version 6.7, which currently aggregates data from 78 data sources (see Supplementary Information). Furthermore, the search functionality on the Pharos web server has been upgraded to use the graph querying language (GraphQL; https://graphql.org/) API that facilitates faster data retrieval, directly from TCRD.
