Injection drug use provides an efficient mechanism for transmitting bloodborne viruses, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV). In the United States (U.S.), 8% of all new HIV infections in 2010 were among persons who inject drugs (PWID) and 3% were among PWID who also engaged in male-male sex [1]. In 2010, PWID comprised 22% of adults and adolescents living with HIV infection in the United States [2]. PWID are estimated to comprise about 16% of persons with acute HBV infection [3]. A national probability survey, conducted from 1999 through 2002, showed that 48% of adults aged 20–59 years who tested antibody positive for HCV reported a history of injection drug use [4].