Chunk #10 — Materials and Methods — COGA case-control sample — Analyses

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Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations.

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We used the program PLINK (Purcell et al., 2007, Chang et al., 2015) to run set-based analyses for alcohol dependence diagnosis. The p-value threshold used in set-based analyses was 0.01, and the r2 threshold for LD pruning was set to 0.5. Gender and two race principal components were used as covariates.