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Chunk #24 — 2. Materials and methods — 2.4. Statistical analysis

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Priming deficiency in male subjects at risk for alcoholism: the N4 during a lexical decision task.
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Data were analyzed using SPSS version 12.0. Of the 19 channels, data from nine electrodes were selected and grouped into three regions, viz. frontal (Fz, F3, F4), central (Cz, C3, C4), and parietal (Pz, P3, P4). Subject and task related variables such as age, average alcohol intake (number of drinks) per month for the last six months, number of correct responses, and reaction time were analyzed for group differences using student’s t test and paired samples t test. As a primary analysis, repeated measures ANCOVAs were used separately for amplitude and latency, with groups as the between-subjects variable. Semantic condition (primed and unprimed) and scalp region (frontal, central, and parietal) were entered as the within-subjects factors with average alcohol intake per month for the last six months as covariate. As a secondary analysis, group differences were examined using separate repeated measures ANCOVAs for different semantic conditions (primed-amplitude, primed-latency, unprimed-amplitude, and unprimed-latency). For all the secondary analyses, scalp region and electrode position were entered as within-subjects factors and average alcohol intake per month for the last six months as covariate. Greenhouse-Geisser correction was employed when required. Unless otherwise mentioned the results were non-significant and mean values indicated are covariate-adjusted.