It is tempting to speculate that the consistency of the classification success reported might point to EEG coherence as a possible future diagnostic test for ASD. However, clinical patients are seldom referred just to confirm that they are either neuro-typical or warranting the diagnosis of ASD. Rather, they are referred to establish a diagnosis from among a wide range of clinical possibilities that may produce clinical presentations superficially similar to ASD, including ASD itself. Before entertaining general clinical applicability, the discriminant process will need to be extended to correctly classify conditions beyond the simple C- versus ASD-group dichotomy. Further analyses must encompass diagnoses often associated with or closely related to classic ASD, such as GDD, Asperger's syndrome, developmental dysphasia, childhood disintegrative disorder and autistic behavior as a presenting symptom of other clinical diagnoses, for example, Rett's syndrome, Angelman's syndrome, tuberous sclerosis and Fragile X syndrome.
