Chunk #19 — Results — GABRA2 variants and the Impulsiveness facet of the Neuroticism domain (NEO-PI)

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Impulsiveness mediates the association between GABRA2 SNPs and lifetime alcohol problems.

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Homozygotes for the minor haplotype (CCGG/CCGG) showed significantly higher scores of impulsiveness (p = 0.001) (Table 2) but the haplotype was not a better variable than the most significant SNP alone.