Chunk #15 — Materials and Methods — Statistical analysis — Conditional association analysis

Source

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans.

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To identify additional association signals after accounting for the known loci, we ran conditional analyses, in which we included the significant allele counts at the conditioning loci as covariates to calculate conditional p values for EAs and AAs. We adjusted for the effect of rs1229984 in the EA samples and for rs2066207 in the AA samples, the two peak significant SNPs in those populations.