We identified multiple significant loci on chromosome 4 for MaxDrinks in both EA and AA populations. Within a 236 kb region on chromosome 4, one SNP was significantly associated with MaxDrinks in EAs, and eight SNPs were significantly associated in AAs (Table 2). Three of the nine SNPs were uniquely associated with MaxDrinks; the other six were also strongly associated with AD in our previous study (Gelernter et al., 2014). In the present study, the significant signals were mostly driven by the Yale-UPenn sample.
