network alone,58 suggesting that network-based patterns which are sensitive to decreases and increases may prove more specific to a given disease. Studies of structural connectivity in bvFTD support the disruption of specific frontal-temporal WM tracts, such as the bilateral uncinate and anterior cingulate tracts.66,86 The FTD language syndromes (PPAs) have not yet been directly investigated with resting-state network mapping, however atrophy-mapping studies suggest that they are likewise associated with degeneration of specific networks.84 DTI studies indeed support the disruption of specific WM tracts within the PPA-targeted networks.86,87
