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Chunk #31 — OVERVIEW OF STATISTICAL METHODS — 2. Analysis of Incident Detection and/or Persistence of HPV — Standard Cox Models

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Marginal and mixed-effects models in the analysis of human papillomavirus natural history data.
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However, model (1.7) can not simultaneously analyze time to first incident detection of several different types of HPV, because it does not address possible correlations between incident HPV infections. Instead, it is often more efficient to use methods that can simultaneously assess multiple types of HPV as separate endpoints in a single model. There are two main statistical methods appropriate for this purpose, as follows.