Table 1 shows the genotype frequencies for the 12 SNPs included in the study. The frequencies and LD between SNPs were similar to those calculated in the HapMap CEU sample (available in the International HapMap Genome Browser B36). Eleven SNPs had a minor genotype frequency of less than 0.1 (see Table 1). Participants in these groups were combined with the heterozygous group in the analysis. Only one SNP, rs4274224, was analyzed using all three genotype groups. All SNPs were in Hardy–Weinberg equilibrium. D′ values between the 12 polymorphisms are shown in Figure 1. We formed two haplotype blocks: Haplotype Block 1 contained SNPs rs2242592, rs1079596, rs1125394, and rs27471857; and Haplotype Block 2 contained rs4648317, rs4350392, rs1799978, and rs12364283. SNPs rs71003679, rs4648318, rs4274224, and rs4581480 were not part of any haplotype block.
