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Chunk #6 — Experimental — Materials

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A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability.
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Anti-mu C is a rabbit polyclonal anti-MOR antibody generated as described in our previous reports [26,27] against the sequence CT383NHQLENLEAETAPLP398 (the mu C peptide), which corresponds to the last 16 amino acids (383-398) of the C-terminal domain predicted from the cloned rat MOPR (GenBank: NM_013071) and which is identical among human, rat and mouse. The antiserum was generated in rabbits and purified by use of the mu C peptide affinity chromatography,