for nearly all of the daily fluid intake for HAP mice with consumption > 20 g/kg/day of alcohol and blood alcohol concentrations measured ~80–225 mg/dl, 80 mg/dl being equivalent to the legal driving limit in the United States (Matson & Grahame 2013). LAP mice on the other hand, became virtually complete abstainers and consumed < 5% of their daily fluid from the alcohol tube and had no measurable blood alcohol concentrations following access. The HAP and LAP lines thus model genetic propensities for excessive alcohol consumption (HAP) or avoidance (LAP).
